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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHC1
All Species:
7.58
Human Site:
T386
Identified Species:
18.52
UniProt:
P29353
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29353
NP_001123512.1
583
62822
T386
P
T
A
P
N
A
Q
T
P
S
H
L
G
A
T
Chimpanzee
Pan troglodytes
XP_513843
473
51606
K325
V
N
V
Q
N
L
D
K
A
R
Q
A
V
G
G
Rhesus Macaque
Macaca mulatta
XP_001112447
583
62797
T386
S
T
A
P
S
A
Q
T
P
S
H
L
G
A
T
Dog
Lupus familis
XP_547561
576
62206
T379
P
T
P
H
V
V
Q
T
P
S
H
L
G
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P98083
579
62589
M382
P
T
L
P
S
A
Q
M
S
S
H
L
G
A
T
Rat
Rattus norvegicus
Q5M824
469
51485
K321
V
N
I
Q
N
L
D
K
A
R
Q
A
G
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512200
548
59956
G354
P
G
L
P
W
G
A
G
Q
T
C
D
G
Y
L
Chicken
Gallus gallus
XP_428819
632
69780
E402
F
A
A
G
V
R
R
E
K
I
Y
Y
Q
N
R
Frog
Xenopus laevis
Q8AY68
465
51711
D317
N
R
P
D
L
F
D
D
P
S
Y
V
N
V
Q
Zebra Danio
Brachydanio rerio
XP_001921625
593
63809
P406
L
V
D
M
R
T
R
P
G
H
S
T
G
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
99.1
94.3
N.A.
94.5
76.8
N.A.
48.8
46.8
64.6
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.9
99.4
96.2
N.A.
96.7
78.3
N.A.
62.6
62.5
69.9
76.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
73.3
N.A.
73.3
13.3
N.A.
20
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
73.3
N.A.
80
13.3
N.A.
26.6
20
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
0
0
30
10
0
20
0
0
20
0
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
30
10
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
10
0
10
10
0
0
0
70
20
20
% G
% His:
0
0
0
10
0
0
0
0
0
10
40
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
20
10
0
0
0
0
0
0
% K
% Leu:
10
0
20
0
10
20
0
0
0
0
0
40
0
0
10
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
10
20
0
0
30
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
40
0
20
40
0
0
0
10
40
0
0
0
0
10
0
% P
% Gln:
0
0
0
20
0
0
40
0
10
0
20
0
10
0
10
% Q
% Arg:
0
10
0
0
10
10
20
0
0
20
0
0
0
0
10
% R
% Ser:
10
0
0
0
20
0
0
0
10
50
10
0
0
0
0
% S
% Thr:
0
40
0
0
0
10
0
30
0
10
0
10
0
0
50
% T
% Val:
20
10
10
0
20
10
0
0
0
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
20
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _